Study Suggests Young Men Who Take Ibuprofen May Risk Infertility

Study Suggests Young Men Who Take Ibuprofen May Risk Infertility

"Ibuprofen puts a severe damper on testosterone production, so the brain has to kick in", said David Møbjerg Kristensen, a senior researcher at the Copenhagen's main hospital, Rigshospitalet. And, while testosterone levels are normal during compensated hypogonadism, it's not a good condition to have. And the problem is not likely to be ibuprofen-specific, as most NSAIDs work through similar mechanisms. Bernard Jégou, co-author and director of the Institute of Research in Environmental and Occupational Health in France said that this study was part of another ongoing study that was looking at effects of this drug on pregnant women.

Luteinizing hormone is released by the pituitary gland and causes the testicles to release testosterone. (In culture, there are no cells to produce luteinizing hormone to compensate.) The researchers found that a number of genes involved in steroid synthesis were affected by ibuprofen. Particularly in western countries, where some counts have drastically plunged over the last 40 years. "Ibuprofen is a very useful drug for acute pain conditions, its benefits have been well proven, but it is important to consider that hypogonadism may be an additional risk factor that people need to watch for when taking the drug for a long time", he said.

The best way to address a low testosterone level is with artificial hormones.

To avoid these side-effects, doctors caution against taking Ibuprofen for more longer than ten days in a row, per the FDA's warning.

Such a condition is the result of the body increasing testosterone production because the testes stop producing adequate levels of it.

The study's findings come at a time when male infertility has become a big issue.

According to a separate study, at least 30 million men around the world are infertile, and of the 48.5 million couples that are impacted by infertility, 20-30 percent are reportedly to be found "solely responsible".

Other treatments include hormone replacement, treatments for sexual intercourse problems such as erectile dysfunction and premature ejaculation, and assisted reproductive technology where sperm is injected directly into the female genital tract or used to perform in vitro fertilization.

Compensated hypogonadism occurs before any obvious sypmtoms develop.

Scientists said the health effects of the over-the-counter painkiller "required further investigation, given its widespread use for aches, pains, fever and arthritis, as well as its popularity among athletes", reports The Times.

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